Institute Scientist and director of computational chemical biology research, with expertise in bioinformatics, chemistry, and computational biology, and a strong drive to achieve effective summarization
Paul is an Institute Scientist and director of computational chemical biology research at the Broad Institute, and he acts as a chemical biology translator. Paul and his team of six researchers develop and use tools to convert the shape or biological performance of a compound into a series numbers (vectors) that a computer can interpret. Using math and statistics, his team can find compounds that are similar to a compound of interest, determine how diverse a collection of small molecules is, interpret the relationship between a compound’s chemical structure and the way it performs against a protein target or in cells, and much more. In addition to his expertise in bioinformatics, cheminformatics, and computational biology, Paul spends a considerable amount of time optimizing his – and others’ – research communication. He does so through effective summarization, figures, and slides; understanding and catering to one’s audience, and; editorial perfectionism.